BPC-157 / TB-500 (TB4) Blend (10mg)
$ 67.50
Description The BPC-157 / TB-500 Blend is a composite peptide formulation. It combines two distinct synthetic peptides: BPC-157 (Body Protection Compound-157), a partial sequence of a human gastric protein, and TB-500, a synthetic analogue of the naturally occurring protein Thymosin Beta-4. Researchers utilize this blend to investigate the intersection of multiple regenerative pathways simultaneously. Specifically, experimental workflows employ this combination to quantify effects on angiogenesis, actin polymerization dynamics, and the migration of endothelial or stromal cells in complex tissue engineering models. Unlike single-molecule controls, this blend allows for the assessment of potential synergistic mechanisms involving the nitric oxide (NO) system and cytoskeletal motility regulators. Biochemical Characteristics Chemically, this reagent represents a mixture of a pentadecapeptide (BPC-157) lacking a distinct tertiary structure, and a 43-amino acid peptide (Thymosin Beta-4) known for its flexible, unfolded nature in solution which facilitates actin binding. Sequence/Structure: Heterogeneous mixture of BPC-157 (15 amino acids) and Thymosin Beta-4/TB-500 (43 amino acids). Permeability: Both components exhibit specific cellular interaction profiles; BPC-157 is studied for its stability in gastric juice models, while TB-500 interacts with intracellular actin pools. Stability: Supplied as a co-lyophilized salt to ensure long-term stability and prevent hydrolytic degradation or peptide aggregation during storage. Specificity: Designed to probe distinct receptors and intracellular targets: the NO-cGMP pathway (BPC-157) and G-actin sequestration sites (TB-500). Chemical Properties Property Specification Molecule Name BPC-157 / TB-500 Blend Synonyms Bepecin; PL 14736 / Thymosin Beta-4; Tβ4 PubChem CID 9941957 (BPC-157); 16132341 (TB-4) Molecular Formula Mixture (C62H98N16O22 / C212H350N56O78S) Molecular Weight 1419.5 g/mol (BPC-157) / 4963.5 g/mol (TB-500) Form Lyophilized Powder Purity ≥99% (Verified via HPLC) Solubility Soluble in water and aqueous buffers (refer to SDS) Documentation COA and SDS available per lot
