Tesamorelin / Ipamorelin (6mg/2mg)
$ 99.00
Description Tesamorelin / Ipamorelin (6mg/2mg) is a synergistic synthetic peptide combination research reagent. It is chemically distinct as it blends a 44-amino acid GHRH analog with a targeted pentapeptide ghrelin receptor agonist, utilized in laboratory settings to investigate the dual-pathway stimulation of the hypothalamic-pituitary-somatotropic axis. Researchers employ this combination to study amplified endogenous growth hormone secretion and its specific downstream metabolic endpoints, such as the reduction of visceral fat in lipodystrophy models, positive muscle tissue remodeling, and the counteraction of glucocorticoid-induced bone loss. Biochemical Characteristics Sequence/Structure: Peptide blend; Tesamorelin (44 amino acids modified with a trans-3-hexenoic acid group) and Ipamorelin (Pentapeptide; Aib-His-D-2Nal-D-Phe-Lys-NH2). Permeability: Requires specific receptor interaction on pituitary somatotrophs in cellular models. Stability: Supplied as a lyophilized salt to ensure long-term stability and prevent hydrolytic degradation during storage. Specificity: Highly specific dual-agonist action; Tesamorelin selectively binds the GHRH receptor, while Ipamorelin selectively binds the growth hormone secretagogue receptor (GHSR-1a) without significantly elevating cortisol or prolactin. Chemical Properties Property Specification Molecule Name Tesamorelin / Ipamorelin Synonyms TH9507 (Tesamorelin); NNC 26-0161 (Ipamorelin) PubChem CID 16137828 (Tesamorelin) / 9831024 (Ipamorelin) Molecular Formula C221H366N72O67S / C38H49N9O5 Molecular Weight 5135.9 g/mol / 711.9 g/mol Form Lyophilized Powder Purity $ge99%$ (Verified via HPLC) Solubility Soluble in water and aqueous buffers (refer to SDS) Documentation COA and SDS available per lot
